Ascites production. © 1988-2021,
(Cunliffe-Beamer T, Lab Anim Sci, 1976). J Neurogenet 5(1):61-76, Welkos SL; Keener TJ; Gibbs PH. Outbreds and Closed Colonies 6.1 Outbreds YBR/Ei, 020/A, 129/J, SF/CamEi and SK/CamEi. JAX® Mice strains are only made available to researchers after meeting our standards. As with congenic strains, a minimum of 10 backcross generations is required, counting the F1 generation as generation 1. Mice receiving 0.25, 0.5 and 1 mg/g of body weight by oral gavage had 6.8%, 30.6% and 48% less tumor growth, respectively. Further analysis has shown this is caused by a G to A transition at coding nucleotide position 753 of Cdh23 (SNP rs257098870). ZERO BIAS - scores, article reviews, protocol conditions and more Abbreviation for binaural alternate loudness balance test. This strain is available from some international Charles River (CR) breeding facilities in Japan and/or Europe. Printer friendly. 1987. For more information, see the Worldwide Distributor List for JAX® Mice. The animals were allowed to acclimatize for at least one week. BALB/c mice receiving the Hiltonol® treatments were also significantly effective in protecting mice against weight loss due to infection. For additional variation among BALB/c substrains maintained throughout the world see The BALB/c Mouse. Proc Natl Acad Sci U S A 67(1):377-84, Cheers C; McKenzie IF. Fig. Among mice models of dementia the most used strains are SAMP8 and C57BL/6. Shipment: All shipping destinations qualify. New search features Acronym Blog Free tools "AcronymFinder.com. Differences in susceptibility of inbred mice to Bacillus anthracis. Such a strain is developed by crossing male C57BL/6J mice with BALB/c females, followed by repeated backcrossing of female offspring to male C57BL/6J. Postal codes: USA: 81657, Canada: T5A 0A7. Measuring normal and pathological anxiety-like behaviour in mice: a review. Dementia is defined as cognitive impairment in more than one cognitive area and leads to an abnormal degree of impairment in the ability to remember past events. 1986. Evidence for genetic control of microwave-induced augmentation of complement receptor-bearing B lymphocytes. 2003. It is dependent on the presence of interferon-alpha and -beta but not -gamma (J:7365). Genetics and Immunology, M. Potter (ed. There was an accidental death of BALB/c mice in the course of the experiment about hepatitis B immunization. "global warming"
BALB stands for Bagg Albino (inbred research mouse strain). MPA induces mammary tumors in virgin BALB/c mice with an average latency of 52 weeks. A, BALB, C3H, C57BL, NZB mice and ACI, F344, LEW and M520 rats. with 50 μg αCD70 mAb 1 d before i.p. BALB refers to Bagg Albino (inbred research mouse strain. BALB/c mice are particularly well known for the production of plasmacytomas following injection with mineral oil forming the basis for the production of monoclonal antibodies. As stated above, BALB/c mice play important roles in oncological research. C57BL/6 and BALB/c are the main mouse strains. Low sociability is associated with reduced size of the corpus callosum in the BALB/cJ inbred mouse strain. 11-12 Increases Resistance of BALB/c Mice to Mycobacterium Tuberculosis Infection JoAnne L. Flynn,'* Marsha M. Coldstein: Karla J. Triebold,* Joseph Sypek,* Stanley Wolf,* and Barry R. Bloom* Development of a SNP genotyping panel for genetic monitoring of the laboratory mouse. This large deletion apparently renders the protein incapable of providing resistance to influenza. Resistance is expressed by macrophages and other cells in vitro (J:6649, J:5940) but could not be transferred to susceptible animals by transfer of macrophages from resistant mice (J:6149). Hippocampal lamination defect = Hld. DEN induced squamous cell carcinomas of the forestomach and esophagus in BALB/c mice, as in RF mice, while DMN had no detectable effect on these 2 organs in either strain. Thank you for sharing your feedback! We wondered if these alterations would reverse the immune response in experimental leishmaniasis. In mice, it is usually performed using forced oscillation technique (FOT), negative pressure-driven forced expiratory (NPFE) and pressure-volume (PV) curve … 6. This strain was found to be susceptible to infection by Listeria monocytogenes, with a 3 day median time to death in females (Cheers and McKenzie, 1978). Both BALB/cJ and BALB/cByJ mice can be used to establish ascites tumors. For additional variation among BALB/c substrains maintained throughout the world see The BALB/c Mouse. 1970. The reasons of the mice breeding failure were analyzed in order to provide some experience for future animal preparation about hepatitis B immunization. From the same litter, half of fetus was used for RT-PCR and the other half was frozen down for immunohistochemistry (see below). BALB stands for Bagg Albino (inbred research mouse strain). A GF colony of IL-8Rh-/-mice was established by deriving IL-8Rh-/-pups into the GF state by cesarean section. Terms are granted by individual review and stated on the customer invoice(s) and account statement. Ca substrain susceptible to L. major mexicana, and vaccination against the parasite using liposomes with parasite membrane antigens was effective (cf C57BL/6 but contrast C57BL/10) (Lazama-Davila, 1997). 3 wk later, the frequency of IFN-γ + CD4 + CD3 + splenic T cells was determined by intracellular staining. The data suggest that BALB/c mice may be a better research tool than C57BL/6J mice to study TAC-induced disease progression to HF and to evaluate novel th … Both BALB/cJ and BALB/cByJ mice … The pups were raised to adulthood by GF BALB/c mothers. BALB/c is an albino, immunodeficient inbred strain. Ltx1, a mouse locus that influences the susceptibility of macrophages to cytolysis caused by intoxication with Bacillus anthracis lethal factor, maps to chromosome 11. PSP, HIPAA
Resistant to Leishmania major (contrast BALB/c) (Laskay et al, 1995). Dr. Halsey J. Bagg who started breeding these … Methods: The cytotoxicity of peritoneal macrophages (Mphi) against H22 cells was measured by the radioactivity of ((3)H)TdR assay, mice with H22 tumor were injected with different concentrations of resveratrol, and the inhibitory rates were … Atherosclerosis susceptibility differences among progenitors of recombinant inbred strains of mice. SmGSP and SmIKE reduced the number of eggs trapped in the liver by more than 50% in challenged BALB/c mice. The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. White et al. Mice were maintained on NAC‐containing water 2 days before infection for a total of 14 weeks. 1952. Proc Natl Acad Sci U S A 114(34):9158-9163, monoclonal antibodies, myeloma and hybridoma production, experimental allergic encephalomyelitis (EAE), abnormal hippocampal mossy fiber morphology, this is secondary to a defect in neuronal migration, located below the intrapyramidal layer; some of the ectopic cells have short, fine-caliber dendritic branches arising near the points of contact of the intrapyramidal mossy fibers, cell bodies are located below the intrapyramidal mossy fiber layer, abnormally positioned by being late-generated, abnormal hippocampus CA3 region morphology, there is abnormal lamination of this cell layer resulting in superficial early generated neurons and deep late-generated neurons, Belzung C; Griebel G. 2001. Bagg developed the “Bagg albino” in 1913 from stock from an Ohio pet dealer. Lung function measurement is a key step in such investigation. Derived from albino mice stocks originally disseminated by Bagg (1913) to Snell in 1932 that has an albino coat with genotype A,b,c. Lab Anim Sci 26(5):736-41, Schlagel CJ; Ahmed A. Deletion of IL-4Ralpha in the BALB/c mouse is associated with altered lesion topography and susceptibility to experimental autoimmune encephalomyelitis. Lab Anim Sci 26(6 Pt 1):895-8, Ebbesen P. 1971. The Jackson Laboratory, Charles River Laboratories, Taconic Biosciences, and Harlan Laboratories are the main suppliers. When using the BALBc mouse strain in a publication, please include JAX stock #000651 in your Materials and Methods section. Payment for services, products, shipping containers, and shipping costs that are rendered are expected within the payment terms indicated on the invoice or stated by contract. examined BALB/c mice. Among mice models of dementia the most used strains are SAMP8 and C57BL/6. Although not all BALB/c substrains have been examined for plasmacytoma induction, substrains derived from the Andervont (An) lineage (which includes BALB/cByJ) typically are susceptible, while those descended from BALB/cJ are resistant (see: Potter M, 1985). The resistance allele at the Mx1 locus, under induction by alpha/beta interferon, produces the 75 kDa protein MX-1, which confers resistance to the influenza virus, in the nuclei of cells carrying the allele. Female Balb C Mice, supplied by Pasteur Institute, used in various techniques. Most inbred strains, including C57BL/6J, C3H/HeJ, and BALB/cJ, carry an influenza susceptible Mx1s1 allele which produces mRNA lacking exons 9, 10, and 11 of the Mx1r allele. As with congenic strains, a minimum of 10 backcross generations is required, counting the F1 generation as generation 1. The following inbred strains are homozygous for the recessive QTL, Micrl. The World's most comprehensive professionally edited abbreviations and acronyms database Methods Experimental design A total of twelve male Balb/c mice aged 6 months with an average body weight of 30 (SEM 1)g were obtained from the breeding centre Nutrición y Fisiología (Spanish Government licence: ES280790000085), Faculty of Pharmacy, Universidad TRAIL ( Tnfsf10 /TRAIL/CD253/Apo2L) is an important immune molecule that mediates apoptosis.
Autoimmunity:1-14, Paigen B; Ishida BY; Verstuyft J; Winters RB; Albee D. 1990. Abstract Healing of leishmaniasis—a parasitic skin disease—is associated with high levels of secreted interferon (IFN)γ and IL‐12 in resistant C57BL/6 mice and humans. There are no related strains using this filter. Some unusual genetic characteristics of BALB/c and evidence for genetic variation among BALB/c substrains. These transactions are payable in U.S. currency within the granted terms. Resistance and susceptibility of mice to bacterial infection: genetics of listeriosis. Each animal was intraperitoneally (IP) injected with a mixture of incomplete Freund's adjuvant (IFA) (Sigma-Aldrich, USA) and 100 μg of a combination of rOmp16, rOmp19, rOmp28, and rL7/L12 at a ratio of 1:1:1:1 in a total volume … Bone-marrow-derived macrophages from 2- and 18-month-old (senescent) C57BL/6 or BALB/c mice showed … 1982. The experiment lasted 7 months. Int J Cancer 7(1):141-8, Petkov PM; Cassell MA; Sargent EE; Donnelly CJ; Robinson P; Crew V; Asquith S; Haar RV; Wiles MV. COMMITTEE on Standardized Nomenclature for Inbred Strains of Mice Cancer Res 12(8):602-13, Nowakowski RS. Note that it is incorrect to use a full descriptive name such as “Brown Norway” rather than the correct designation BN. Mice. Differences in tumor incidence in two substrains of Claude BALB/c (BALB/cfCd) mice, emphasizing renal, mammary, pancreatic, and synovial tumors. Variations were also found in the timeline of response and cell types most impacted. Mouse News Lett 71:35, Nowakowski RS. Laboratory routine procedures such as handling, injection, gavage or transportation are stressful events which may influence physiological parameters of laboratory animals and may interfere with the interpretation of the experimental results. BALB/c nude mice inoculated with A549 cells 1 and 2 mg/kg/day (18 days) ↓ Tumor growth  ↓ Tumor volume ↓ Tumor weight ↑ RIP1 protein expression ↑ p-RIP3 protein expression Intact cell nuclei Damaged mitochondria Emodin Rheum palmatum L. BALB/c nude mice inoculated with U251 cells 20, 40 and 80 mg/kg/day (28 days) ↓ Tumor growth Three branches from Snell’s BALB/c were separated during the period 1937-1939, Andervont (BALB/cAn), Scott (BALB/cSc), and Green (BALB/cGn). Balb/c mice (n = 8) were mated and the fetuses were collected at 8 th, 12 th, 16 th 18 th, 20 th GD and 1 DPN. Genetics: Curr Top Microbiol Immunol 122:9-18, Sass B; Peters RL; Kelloff GJ. Charles River BALB/c mice were used to perform parasite infection to study the antiplasmodial immunity in mosquitos . In addition, groups of 20 mice were dosed with Hiltonol® at 2.5 or 0.75 mg/kg/day by intranasal instillation 7, 14, or 21 days before virus exposure, and … redox imbalance and pulmonary function in bleomycin-induced fibrosis in c57bl/6, dba/2, and balb/c mice marco aure´lio santos-silva 1,karla maria pereira pires 1,eduardo tavares lima trajano 1, vanessa martins 2,renata tiscoski nesi 2,cla´udia farias benjamin 2,mauri´cio silva caetano 3, cinthya sternberg 3,mariana nascimento machado 4,walter arau´jo zin 4, samuel santos valenc¸a Previous studies in our laboratory have demonstrated that BALB/c mice are also highly susceptible to infection with virulent B. pseudomallei , while C57BL/6 mice are relatively resistant ( 24 , 32 ). Bioz Stars score: 85/100, based on 55 PubMed citations. The spleen weight of the F 1 mice was lowest without any discernible differences between that of BALB/c and Swiss mice. Mice, viral infection, and experimental design The generation and characterization of IFN-g–KO mice were described previously (27). Mice Immunization and Bacterial Challenge. Deficiency of the corpus callosum: incomplete penetrance and substrain differentiation in BALB/c mice. Myoepitheliomas in inbred laboratory mice. TRAIL can play key roles in regulating cell death in the tumor and autoimmune microenvironments. Farlex Partner Medical Dictionary © Farlex 2012 Want to thank TFD for its existence? Ascites production. 2014. Susceptibility alleles do not produce the protein (J:8273). Am J Physiol Lung Cell Mol Physiol 285(1):L32-42, Zhu W; Gilmour MI. ), Current Topics in a Microbiology and Immunology 122, Springer-Verlag, 1985. Enalapril was effective in improving survival and reducing lung congestion in this model. Such a strain is developed by crossing male C57BL/6J mice with BALB/c females, followed by repeated backcrossing of female offspring to male C57BL/6J. Maruo et al (1982) found that the tumor growth rate of human gastric cancers was high in outbred nude mice (NIH) compared to nude mice on a inbred background (BALB/c, C57BL/6J). In contrast, high incidences of lung tumors were induced in RF mice by both carcinogens. This is a substrain of BALB (Bagg’s albino) derived initially from the BALB strain maintained by MacDowell at Cold Spring Harbor, eventually sent to G.D. Snell at the University of Texas and brought by Snell to the Jackson Laboratory in 1932 at generation F26. The objective of this study was to determine the time duration of this low dose induced MAPK activation in BALB/c mice and to find out if similar adaptive responses are observed in C57BL/6 mice. BALB/c Mouse Details H.J. 2008. Couldn't find the full form or full meaning of BALB? J Neurogenet 1(3):249-58, Nygaard UC; Aase A; Lovik M. 2005. Differential susceptibility to actively induced experimental allergic encephalomyelitis and experimental allergic orchitis among BALB/c substrains. 1998. Although some interferon-induced genes respond directly to virus invasion as well as indirectly through induction by virus-induced interferon, this primary response is very weak for the MX-1 protein in response to either influenza or Newcastle disease viruses (J:1892). Leishmania major infected BALB/c mice were treated with N‐acetyl‐ l ‐cysteine (NAC), a glutathione precursor, to evaluate the role of in vivo glutathione on lesion pathology and cytokine profiles following infection. BALB/csarcoma MethA. Volume Pricing Program
Resistance to infection with two tick-borne viruses, Thogoto virus (J:8273) and Dhori virus (J:27760), is also conferred by Mx1r. Maybe you were looking for one of these abbreviations: BALA - BALANA - BALANCE - BALAS - BALaw - BALBO - BALC - BALCA - BALCO - BALCONY CTLA‐4 and CD28 molecules both bind to B7 molecules on antigen‐presenting cells. Major research applications are in immunology, oncology, physiology, pathology, and neuroscience. There was an accidental death of BALB/c mice in the course of the experiment about hepatitis B immunization. The BALB/c mouse develops plasmacytomas upon injection with mineral oil, which form the mouse cell component of the mouse-human hybrid cells that are used in the production of To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project. Sexes: Sexes of the same strain may be combined to reach minimum quantity levels to receive the volume pricing
Mammary tumors, plaques, and hyperplastic alveolar nodules in various combinations of mouse inbred strains and the different lines of the mammary tumor virus. mice had lesion sizes which were intermediate between those of BALB/c and Swiss mice. BALB: Binaural Alternate Loudness Balance Test: BALB: Bagg Albino (inbred research mouse strain) 1976. Twenty 12-week-old female BALB/c mice were distributed into four groups of five mice each. 1984. BALB/c mice uniformly developed congestive HF post-TAC. Clone 4 or BALB/c mice were transplanted with skin grafts harvested from HA104 mice. The MX-1 protein is a GTPase containing a GTP binding domain (J:1417) and this binding core is also necessary (J:21243). Inbred in 1923 by McDowell. Dorso-ventral vaginal septa is observed in some BALB/cJ females, and may contribute to non-productive females in this strain. Quantities: Volume pricing is automatically applied when a minimum quantity per strain for a shipment is reached
This hypomorphic allele changes splice donor site G-GT to A-GT, causing frame skipping of exon 7. A breeding colony of the BALB/c mice develop other cancers later in life including reticular neoplasms, primary lung tumors, and renal tumors. Three T cell peptides predicted to bind MHC mouse and human class II were synthesized and formulated for vaccination. Previous studies in our laboratory have demonstrated that BALB/c mice are also highly susceptible to infection with virulent B. pseudomallei , while C57BL/6 mice are relatively resistant ( 24 , 32 ). Objective ZAP‐70W163C BALB/c (SKG) mice develop reactive arthritis (ReA) after Chlamydia muridarum (Cmu) infection. 1989 Differential seizure sensitivities to picrotoxinin in two inbred strains of mice (DBA/2J and BALB/c ByJ): parallel changes in GABA receptor-mediated chloride flux and receptor binding. 1984. Oral administration of live Bifidobacterium substrains isolated from healthy centenarians enhanced immune function in BALB/c mice Author links open overlay panel Hai-ying Yang a Song-ling Liu a Salam A. Ibrahim b Liang Zhao a Jing-li Jiang c Wen-feng Sun d Fa-zheng Ren a The BALB/cJ substrain is susceptible to Listeria, all species of Leishmania, and several species of Trypanosoma, but is resistant to experimental allergic orchitis (EAO). either: (involves: BALB/cByJ) or (involves: BALB/cJ), Festing Inbred Strain Characteristics: BALB/c, Additional Breeding and Husbandry Support. To capture interplay between biological pathways, we analyzed the proteome from matched lung tissues and bronchoalveolar lavage fluid (BALF) of individual allergen-naïve and house dust mite (HDM)-challenged BALB/c mice, a model of allergic asthma. Genetic complementation tests have shown allelism between the mdfw (modifier of deaf waddler) locus and the ahl locus. In many of these BALB/c-C57BL/6 models, BALB/c mice are innately susceptible to infection whereas C57BL/6 mice are relatively resistant. Behav Brain Res 136(2):555-69, Teuscher C; Blankenhorn EP; Hickey WF. immunization with 10 μg DEC-LACK, 10 μg 33D1-LACK, 50 μg LACK protein, and 10 μg Ig-LACK in the presence of αCD40 and poly IC, or PBS. The protein is located in the nucleus (J:7703) and produces its antiviral effect by preventing synthesis of viral mRNA in the nucleus (J:7992). The allergy adjuvant effect of particles - genetic factors influence antibody and cytokine responses. Treatment of murine Th1- and Th2-mediated inflammatory bowel disease with NF-kappa B decoy oligonucleotides. 2009. BALB is defined as Bagg Albino (inbred research mouse strain) rarely. Genetic transmission of viruses that incite mammary tumor in mice. ), Current Topics in a Microbiology and Immunology 122, Springer-Verlag, 1985. Behav Brain Res 125(1-2):141-9, Chang B; Hawes NL; Hurd RE; Davisson MT; Nusinowitz S; Heckenlively JR. 2002. BALB/c mice (A and C) or C57/B6 mice (B) were sensitized by FITC (A and B) or DNFB (C) according to protocol A. Anti‐mouse IL‐5 antibody or control antibody were injected at a dose of 500 µg/mouse s.c., control animals received the corresponding volume of PBS 1 h before challenge. What information were you hoping to find through your search? 1978. 1991. Mice Breeding pairs of BALB/c IL-8Rh-/-mice were obtained from Dr. Mark Moore (Genentech, San Francisco, CA). J Natl Cancer Inst 47(6):1241-5, Ewart SL; Kuperman D; Schadt E; Tankersley C; Grupe A; Shubitowski DM; Peltz G; Wills-Karp M. 2000. Tell a friend about us, add a link to this … Am J Respir Cell Mol Biol 23(4):537-45, Fairless AH; Dow HC; Toledo MM; Malkus KA; Edelmann M; Li H; Talbot K; Arnold SE; Abel T; Brodkin ES. In the maximum (+++) response, the major part of thetumormassis destroyed, leavingonlyaperipheralrimof apparentlyviabletumortissue. Key traits include a susceptibility to developing the demyelinating disease upon infection with Theiler's murine encephalomyelitis virus. Aging has been associated with a decline in immunocompetence and resistance to infections, partially due to dysregulated NO production by macrophages and deficits in mounting Th2 cell responses. Resistance is specific for the orthomyxoviruses (J:6265). Retinal degeneration mutants in the mouse. The BALB/c mouse was selected as a model for infection with Brucella abortus on the basis of protracted nonclinical infection produced by strain 2308, virulent for cattle, and relatively rapid clearance of strain 19, an attenuated strain used to vaccinate cattle. The lineage from BALB/cSc eventually became BALB/cJ in 1941 at generation F41. Vet Pathol 28(4):313-23, Tang X; Orchard SM; Sanford LD. Acronym Definition; BALB: Binaural Alternate Loudness Balance Test: BALB: Bagg Albino (inbred research mouse strain) 5.1 Coisogenic Strains. Macrophages from BALB/c and CBA/Ca mice differ in their cellular responses to Streptococcus pneumoniae Vera M. Ripoll,*,1 Aras Kadioglu,† Roger Cox,* David A. Hume,‡ and Paul Denny* *Mammalian Genetics Unit, Medical Research Council, Harwell, United Kingdom; †Department of Infection, Immunity and Inﬂammation, University of Leicester, United Kingdom; and ‡The Roslin … CTLA‐4 (CD152) expression is restricted to subsets of activated T lymphocytes and shares homology with CD28. werebledonce,andthebloodwascollectedin3.8%sointervals after transplantation 10 mice from each group dium citrate (10:1, v/v). BALB/c mice immunized with PLP180-199 develop an atypical form of experimental autoimmune encephalomyelitis (EAE) in which susceptibility is determined by location. Three T cell peptides predicted to bind MHC mouse and human class II synthesized... 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